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Moto Fukai Selected Research

amatuximab

10/2021Early administration of amatuximab, a chimeric high-affinity anti-mesothelin monoclonal antibody, suppresses liver metastasis of mesothelin-expressing pancreatic cancer cells and enhances gemcitabine sensitivity in a xenograft mouse model.
2/2021Mesothelin blockage by Amatuximab suppresses cell invasiveness, enhances gemcitabine sensitivity and regulates cancer cell stemness in mesothelin-positive pancreatic cancer cells.

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Moto Fukai Research Topics

Disease

9Ischemia
07/2020 - 02/2003
8Hepatocellular Carcinoma (Hepatoma)
10/2022 - 11/2015
7Neoplasms (Cancer)
10/2021 - 07/2016
7Reperfusion Injury
07/2020 - 02/2003
4Neoplasm Metastasis (Metastasis)
10/2021 - 05/2017
4Liver Cirrhosis (Hepatic Cirrhosis)
07/2021 - 05/2015
4Inflammation (Inflammations)
03/2016 - 09/2008
3Fibrosis (Cirrhosis)
07/2021 - 11/2015
2Pancreatic Neoplasms (Pancreatic Cancer)
10/2021 - 02/2021
2Non-alcoholic Fatty Liver Disease
07/2021 - 01/2016
2Infections
01/2021 - 11/2015
2Death (Near-Death Experience)
07/2020 - 12/2018
2Liver Diseases (Liver Disease)
10/2019 - 11/2015
2Necrosis
12/2018 - 03/2012
2Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
03/2016 - 03/2012
2Body Weight (Weight, Body)
03/2016 - 05/2006
2Colitis
03/2016 - 03/2012
1Sarcopenia
07/2021
1Peritonitis
02/2021
1Stomach Neoplasms (Stomach Cancer)
02/2021
1Superinfection
01/2021
1Coinfection
01/2021
1Liver Neoplasms (Liver Cancer)
12/2020
1Cholangiocarcinoma
08/2020
1Carcinogenesis
01/2020
1Adenomatous Polyposis Coli (Familial Adenomatous Polyposis)
01/2020
1Heart Arrest (Cardiac Arrest)
12/2018
1Disease Progression
01/2018
1Triple Negative Breast Neoplasms
07/2016

Drug/Important Bio-Agent (IBA)

5Biomarkers (Surrogate Marker)IBA
02/2021 - 11/2015
3CytokinesIBA
03/2016 - 03/2012
2Glycoproteins (Glycoprotein)IBA
10/2021 - 02/2021
2amatuximabIBA
10/2021 - 02/2021
2MesothelinIBA
10/2021 - 02/2021
2GemcitabineFDA Link
10/2021 - 02/2021
2Fatty Acid-Binding ProteinsIBA
01/2021 - 05/2017
2Glutathione Disulfide (GSSG)FDA LinkGeneric
11/2019 - 05/2005
2SolutionsIBA
11/2019 - 12/2018
2EnzymesIBA
11/2019 - 12/2018
2HydrogenIBA
12/2018 - 12/2016
2Messenger RNA (mRNA)IBA
03/2016 - 03/2012
2InterleukinsIBA
03/2016 - 03/2012
2Therapeutic UsesIBA
05/2015 - 03/2012
2NF-kappa B (NF-kB)IBA
03/2012 - 09/2008
2dehydroxymethylepoxyquinomicinIBA
03/2012 - 09/2008
1Versicans (Versican)IBA
10/2022
1Monoclonal AntibodiesIBA
10/2021
1Immunoglobulin G (IgG)IBA
10/2021
1LuciferasesIBA
10/2021
1MyostatinIBA
07/2021
1Keratins (Keratin)IBA
02/2021
1Cadherins (E-Cadherin)IBA
02/2021
1sodium-bile acid cotransporterIBA
01/2021
1Antiviral Agents (Antivirals)IBA
01/2021
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
01/2021
1Janus Kinase InhibitorsIBA
01/2021
1Plasminogen Activators (Plasminogen Activator)IBA
12/2020
1Immune Checkpoint InhibitorsIBA
08/2020
1TaurineFDA Link
07/2020
1Deoxycholic Acid (Sodium Deoxycholate)IBA
07/2020
1Carrier Proteins (Binding Protein)IBA
01/2020
1Small Interfering RNA (siRNA)IBA
01/2020
1Glutathione (Reduced Glutathione)IBA
11/2019
1Deuterium Oxide (Heavy Water)IBA
11/2019
1Factor VIII (Coagulation Factor VIII)IBA
10/2019
1Epidermal Growth Factor (EGF)IBA
10/2019
1milk fat globuleIBA
10/2019
1dicarboxydine (DCD)IBA
12/2018
1HLA-A Antigens (HLA-A)IBA
01/2018
1Phosphotransferases (Kinase)IBA
01/2017
1Sorafenib (BAY 43-9006)FDA Link
01/2017
1Dextran SulfateIBA
03/2016
1Ethanol (Ethyl Alcohol)IBA
03/2016
1Anti-Inflammatory Agents (Anti-Inflammatories)IBA
03/2016
1LipopolysaccharidesIBA
03/2016
1Peroxidase (Myeloperoxidase)IBA
03/2016
1Trinitrobenzenesulfonic AcidIBA
03/2016
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2016
1glutarimideIBA
03/2016
1Macrophage Colony-Stimulating FactorIBA
01/2016
1ChemokinesIBA
01/2016
1Hyaluronic Acid (Hyaluronan)IBA
01/2016
1Collagen Type IV (Type IV Collagen)IBA
01/2016
1Proteins (Proteins, Gene)FDA Link
11/2015
1wisteria lectinIBA
11/2015
1Alanine Transaminase (SGPT)IBA
11/2015
1Indocyanine Green (Cardio-Green)FDA LinkGeneric
11/2015
1BilirubinIBA
11/2015
1AlbuminsIBA
11/2015
1CD40 Ligand (CD40L)IBA
07/2015
1sodium bisulfide (NaHS)IBA
07/2015
1Hydrogen Sulfide (Sulfide, Hydrogen)IBA
07/2015

Therapy/Procedure

5Therapeutics
10/2021 - 01/2017
2Transplantation
07/2020 - 05/2015
2Warm Ischemia
07/2020 - 05/2005
1Adjuvant Chemotherapy
10/2021
1Lasers (Laser)
12/2020
1Aftercare (After-Treatment)
10/2019
1Precision Medicine
01/2018
1Neoadjuvant Therapy
07/2016